• Source: Wee1-like protein kinase

WEE1 homolog (S. pombe), also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.




Function


This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.




Interactions


Wee1-like protein kinase has been shown to interact with YWHAB and PIN1.




References






Further reading






External links


WEE1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• Wee1-like protein kinase
• Wee1
• Protein kinase domain
• AMP-activated protein kinase
• Protein kinase C
• P38 mitogen-activated protein kinases
• Protein kinase B
• Tyrosine kinase inhibitor
• Mitogen-activated protein kinase
• Myotonin-protein kinase