- Source: X-linked hypertrichosis
X-linked hypertrichosis, also known as X-linked congenital generalized hypertrichosis, is a hereditary disorders characterized by generalized congenital hypertrichosis and thick eyebrows.
Signs and symptoms
Hypertrichosis is characterized as excessive hair growth anywhere on the body, in either men or women. X-linked hypertrichosis affects males more than females.
Causes
X-linked hypertrichosis was first mapped in chromosome Xq24-q27.1 in a Mexican family; however, the underlying genetic facts remain unknown. X-linked hypertrichosis is inherited in an X-linked dominant pattern of inheritance.
See also
Generalized hyperhidrosis
List of cutaneous conditions
Further reading
DeStefano, Gina M.; Fantauzzo, Katherine A.; Petukhova, Lynn; Kurban, Mazen; Tadin-Strapps, Marija; Levy, Brynn; Warburton, Dorothy; Cirulli, Elizabeth T.; Han, Yujun; Sun, Xiaoyun; Shen, Yufeng; Shirazi, Maryam; Jobanputra, Vaidehi; Cepeda-Valdes, Rodrigo; Cesar Salas-Alanis, Julio; Christiano, Angela M. (2013-05-07). "Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis". Proceedings of the National Academy of Sciences. 110 (19): 7790–7795. doi:10.1073/pnas.1216412110. ISSN 0027-8424. PMC 3651487. PMID 23603273.
Figuera, Luis E.; Pandolfo, Massimo; Dunne, Patrick W.; Cantú, Jose M.; Patel, Pragna I. (1995). "Mapping of the congenital generalized hypertrichosis locus to chromosome Xq24–q27.1". Nature Genetics. 10 (2). Springer Science and Business Media LLC: 202–207. doi:10.1038/ng0695-202. ISSN 1061-4036. PMID 7663516.