• Source: ZFYVE27

Zinc finger, FYVE domain containing 27 is a protein that in humans is encoded by the ZFYVE27 gene.




Function


This gene encodes a protein with several Transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote Neurite formation. A mutation in this gene has been reported to be associated with Hereditary spastic paraplegia, however the Pathogenicity of the mutation, which may simply represent a Polymorphism (biology), is unclear. [provided by RefSeq, Mar 2010].




References






Further reading



This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Kata Kunci Pencarian:

• ZFYVE27
• Hereditary spastic paraplegia
• FYVE domain
• List of human protein-coding genes 4
• REEP5
• List of OMIM disorder codes