Adhesion molecule (immunoglobulin-like) GudangMovies21 Rebahinxxi LK21

      In molecular biology, the adhesin molecule (immunoglobulin-like) is a protein domain. This domain is found in mucosal vascular addressin cell adhesion molecule 1 proteins (MAdCAM-1). These are cell adhesion molecules expressed on the endothelium in mucosa that guide the specific homing of lymphocytes into mucosal tissues. MAdCAM-1 belongs to a subclass of the immunoglobulin superfamily (IgSF), the members of which are ligands for integrins. The crystal structure of this domain has been reported; it adopts an immunoglobulin-like beta-sandwich structure, with seven strands arranged in two beta-sheets in a Greek-key topology.


      See also


      Bacterial adhesin
      Cell adhesion
      Fungal adhesin


      References

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    Immunoglobulin-like Cell Adhesion Molecules | Cell Biology | JoVe

    Immunoglobulin-like Cell Adhesion Molecules | Cell Biology | JoVe

    Figure 3 from The Immunoglobulin-Like Cell Adhesion Molecule Nectin and ...

    Figure 3 from The Immunoglobulin-Like Cell Adhesion Molecule Nectin and ...

    Figure 3 from The Immunoglobulin-Like Cell Adhesion Molecule Nectin and ...

    Figure 3 from The Immunoglobulin-Like Cell Adhesion Molecule Nectin and ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    Intercellular adhesion molecule - Proteopedia, life in 3D

    Intercellular adhesion molecule - Proteopedia, life in 3D

    (PDF) A Single Immunoglobulin-like Domain of the Human Neural Cell ...

    (PDF) A Single Immunoglobulin-like Domain of the Human Neural Cell ...

    Immunoglobulin superfamily of adhesion molecules | Download Scientific ...

    Immunoglobulin superfamily of adhesion molecules | Download Scientific ...

    Frontiers Roles Of Intercellular Cell Adhesion Molecule-1, 47% OFF

    Frontiers Roles Of Intercellular Cell Adhesion Molecule-1, 47% OFF

    Pharmacological Approaches to Target Immunoglobulin-like Cell Adhesion ...

    Pharmacological Approaches to Target Immunoglobulin-like Cell Adhesion ...

    Pharmacological Approaches to Target Immunoglobulin-like Cell Adhesion ...

    Pharmacological Approaches to Target Immunoglobulin-like Cell Adhesion ...

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    adhesion molecule immunoglobulin like

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    Adhesion molecule (immunoglobulin-like) - Wikipedia

    In molecular biology, the adhesin molecule (immunoglobulin-like) is a protein domain. This domain is found in mucosal vascular addressin cell adhesion molecule 1 proteins (MAdCAM-1). These are cell adhesion molecules expressed on the endothelium in mucosa that guide the specific homing of lymphocytes into mucosal tissues .

    Cell adhesion molecule - Wikipedia

    There are four major superfamilies or groups of CAMs: the immunoglobulin super family of cell adhesion molecules (IgCAMs), Cadherins, Integrins, and the Superfamily of C-type of lectin-like domains proteins (CTLDs). Proteoglycans are also considered to be a class of CAMs.

    Cell Adhesion Molecules and Their Roles and Regulation in the …

    Adhesion molecules are generally divided into five groups: integrins (discussed in greater detail below), selectins, cadherins, members of the immunoglobulin superfamily (IgSF) including nectins and others such as mucins (9).

    The Role of Immunoglobulin Superfamily Cell Adhesion …

    Adhesion molecules belonging to the immunoglobulin superfamily (Ig-SF) commonly play a central role in cell-cell adhesion, and a number of these molecules have been associated with cancer progression and a metastatic phenotype.

    What are immunoglobulin superfamily cell adhesion molecules?

    Nov 30, 2023 · Members of the Immunoglobulin superfamily include vascular and neural cell adhesions molecules (VCAM and NCAM), intercellular adhesion molecules (ICAM) and the Nectins and nectin-like (Necl) proteins.

    Cell Adhesion Molecules and Ubiquitination—Functions and

    Oct 28, 2021 · Cell adhesion molecules of the immunoglobulin (Ig) superfamily represent the biggest group of cell adhesion molecules. They have been analyzed since approximately 40 years ago and most of them have been shown to play a role in …

    Immunoglobulin Superfamily Cell Adhesion Molecules

    Jan 1, 2024 · Many IgCAMs act as cell adhesion molecules. The mode of adhesion mediated by Ig-like domains is divalent and cation-independent, whereas other neural adhesion molecules such as cadherins and integrins require Ca 2+ or Mg 2+ for their adhesive functions.

    The immunoglobulin-like cell adhesion molecule nectin and its ...

    Nectins are immunoglobulin-like cell adhesion molecules (CAMs) that compose a family of four members. Nectins homophilically and heterophilically interact in trans with each other to form cell-cell adhesions.

    Nectin/PRR: an immunoglobulin-like cell adhesion molecule …

    May 3, 1999 · PRR showed Ca2+-independent cell-cell adhesion activity. These results indicate that PRR is a cell-cell adhesion molecule of the immunoglobulin superfamily which is recruited to cadherin-based cell-cell AJs through interaction with afadin.

    Cell Adhesion Molecule - an overview | ScienceDirect Topics

    Proteins of the immunoglobulin superfamily that play a role in adhesion are called Ig-cellular adhesion molecules (Ig-CAMs). Their Ig-like, globular, loop structures are stabilized by sulfydryl bridges and are resistant to proteases ( Figure 13.3a ).