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      The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling proteins) secreted by adipose tissue. Some contribute to an obesity-related low-grade state of inflammation or to the development of metabolic syndrome, a constellation of diseases including, but not limited to, type 2 diabetes, cardiovascular disease and atherosclerosis. The first adipokine to be discovered was leptin in 1994. Since that time, hundreds of adipokines have been discovered.
      Members include:

      Leptin
      Adiponectin
      Apelin
      chemerin
      interleukin-6 (IL-6)
      monocyte chemotactic protein-1 (MCP-1)
      plasminogen activator inhibitor-1 (PAI-1)
      retinol binding protein 4 (RBP4)
      tumor necrosis factor
      visfatin
      omentin
      vaspin (SERPINA12)
      progranulin
      CTRP-4
      Interleukin 8 (IL-8), interleukin 10 (IL-10), interferon gamma (IFN-γ) and inducible protein 10 (IP-10 or CXCL10) have been shown to be associated with excessive body weight.


      See also


      Adipose tissue
      Hepatokines
      Myokines


      Notes




      External links


      Adipokines at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

    Kata Kunci Pencarian:

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    Adipokine | PPT

    Adipokine | PPT

    Adipokine - Creative Diagnostics

    Adipokine - Creative Diagnostics

    Changes and differences of adipokine profiles | Download Scientific Diagram

    Changes and differences of adipokine profiles | Download Scientific Diagram

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    Adipokine-mediated autophagy on tumor cell characteristics during ...

    Figure 1 from The “ Adipokine ” Adiponectin and Metabolic Regulation ...

    Figure 1 from The “ Adipokine ” Adiponectin and Metabolic Regulation ...

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    Important variations of plasma adipokine concentrations and implicated ...

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    Distinct adipokine expression in responders and non-responders. (A ...

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    Adipokine pathways and effects on (A) endothelial cells, (B) vascular ...

    Adipokine - YouTube

    Adipokine - YouTube

    Adipokines | Semantic Scholar

    Adipokines | Semantic Scholar

    Shared biological mechanisms of depression and obesity: focus on ...

    Shared biological mechanisms of depression and obesity: focus on ...

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