- Mieloperoksidase
- Azurophilic granule
- Granule (cell biology)
- Granule
- Neutrophil
- Myeloperoxidase
- Granulocyte
- Myelodysplastic syndrome
- Neutrophil extracellular traps
- Neutrophil-specific granule deficiency
- Monoblast
azurophilic granule
Video: azurophilic granule
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An azurophilic granule is a cellular object readily stainable with a Romanowsky stain. In white blood cells and hyperchromatin, staining imparts a burgundy or merlot coloration. Neutrophils in particular are known for containing azurophils loaded with a wide variety of anti-microbial defensins that fuse with phagocytic vacuoles. Azurophils may contain myeloperoxidase, phospholipase A2, acid hydrolases, elastase, defensins, neutral serine proteases, bactericidal permeability-increasing protein, lysozyme, cathepsin G, proteinase 3, and proteoglycans.
Azurophil granules are also known as "primary granules".
Furthermore, the term "azurophils" may refer to a unique type of cells, identified only in reptiles. These cells are similar in size to so-called heterophils with abundant cytoplasm that is finely to coarsely granular and may sometimes contain vacuoles. Granules may impart a purplish hue to the cytoplasm, particularly to the outer region. Occasionally, azurophils are observed with vacuolated cytoplasm.
See also
Azure A
Azure (color)
Granule
Lysosome
Specific granules
Neutrophil degranulation