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Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers.
Entinostat inhibits class I HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, respectively.
Syndax pharmaceuticals currently holds the rights to entinostat and recently received $26.6 million in funds to advance treatments of resistant cancers using epigenetic tools.
It has also been investigated as a potential male contraceptive drug.




References

Kata Kunci Pencarian:

• Entinostat
• Benzamide
• Histone deacetylase inhibitor
• List of chemotherapeutic agents
• Ketone bodies
• Fluorouracil
• Vincristine
• Chemotherapy-induced nausea and vomiting
• C21H20N4O3
• List of drugs: Em–Ep

Entinostat - LKT Labs

Entinostat - Syndax

Entinostat - Syndax

Entinostat - Syndax

File:Entinostat.png - Wikimedia Commons

Entinostat | C21H20N4O3 | CID 4261 - PubChem

Entinostat « New Drug Approvals

Entinostat « New Drug Approvals

Entinostat « New Drug Approvals

Thermo Scientific Entinostat 1 g:Protein Analysis Reagents | Fisher ...

209783-80-2/Entinostat/chemrenblock supply

Entinostat cancer drug molecule - Stock Image - F018/3016 - Science ...