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Fatty acid-binding protein, epidermal is a protein that in humans is encoded by the FABP5 gene.




Function


This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
The phytocannabinoids (THC and CBD) inhibit endocannabinoid anandamide (AEA) uptake by targeting FABP5, and competition for FABPs may in part or wholly explain the increased circulating levels of endocannabinoids reported after consumption of cannabinoids. Results show that cannabinoids inhibit keratinocyte proliferation, and therefore support a potential role for cannabinoids in the treatment of psoriasis.




Interactions


FABP5 has been shown to interact with S100A7.




References






Further reading

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/2
• FABP5
• Bing Li (academic)
• Astrocyte
• Fatty acid-binding protein
• List of human protein-coding genes 2
• Stress granule
• Endocannabinoid transporter
• CRABP1
• P-bodies
• Lipocalin

FABP5 Promotes Lipid Metabolis [IMAGE] | EurekAlert! Science News Releases

COA of FABP5-IN-1 | Certificate of Analysis | AbMole BioScience

Human Fatty Acid-Binding Protein 5 (FABP5) Antibody | Assaypro

Anticancer FABP5 Inhibitors | Ojima Research Group

Fabp5-IN-1 | C34H30O6 | CID 130428421 - PubChem

FABP5 Protein Overview | Sino Biological

FABP5 Protein Overview | Sino Biological

FABP5 Antibody Supplier | CAS | AOBIOUS

FABP5 Antibody Supplier | CAS | AOBIOUS

Anti-FABP5 Antibody | RayBiotech

Anti-FABP5 antibody (ab84028) | Abcam

Human FABP5/E-FABP Antibody MAB3077: R&D Systems