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  • Source: Glutaconyl-CoA

    • Glutaconyl-CoA is an intermediate in the metabolism of lysine. It is an organic compound containing a coenzyme substructure, which classifies it as a fatty ester lipid molecule. Being a lipid makes the molecule hydrophobic, which makes it insoluble in water. The molecule has a molecular formula of C26H40N7O19P3S, and a molecular weight 879.62 grams per mole.
    Glutaconyl-CoA is postulated to be the main toxin in glutaric aciduria type 1. In certain fermentative bacteria, glutaconyl-CoA decarboxylation is catalyzed by a Na+-dependent decarboxylase (EC 7.2.4.5) and is coupled with Na+ ion translocation, which creates a sodium-motive force as an alternate energy source for these organisms.


    See also


    Glutaconate CoA-transferase
    Glutaconyl-CoA decarboxylase


    References

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glutaconyl coaglutaconyl coa decarboxylase