- Sindrom Klinefelter
- Harry Klinefelter
- Klinefelter syndrome
- Klinefelter
- Johns Hopkins School of Medicine
- List of eponymous diseases
- 1942 in science
- Patricia Jacobs
- Deaths in February 1990
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Harry Fitch Klinefelter Jr. (; March 20, 1912 – February 20, 1990) was an American rheumatologist and endocrinologist. Klinefelter syndrome is named after him.
Biography
Born March 20, 1912, in Baltimore, Klinefelter studied first at the University of Virginia, Charlottesville, and then attained his medical degree from Johns Hopkins School of Medicine. After his graduation in 1937 he continued his training in internal medicine at the Johns Hopkins Hospital. Klinefelter worked at the Massachusetts General Hospital in Boston from 1941 to 1942; under the supervision of Fuller Albright he described a group of nine men with "gynecomastia, aspermatogenesis without aleydigism, and increased excretion of follicle-stimulating hormone", the first description of what would be called the Klinefelter syndrome. Initially he suspected this to be endocrine disorder and postulated the presence of a second testicular hormone, but in 1959, Patricia A. Jacobs and J. A. Strong (Western General Hospital and University of Edinburgh) demonstrated that a male patient with the phenotype of Klinefelter syndrome had an additional X chromosome (47 XXY). Klinefelter confirmed, later, that the cause was chromosomal, rather than hormonal.
Klinefelter served in the Armed Forces from 1943 to 1946 and then returned to Johns Hopkins where he remained during his professional life. In 1966, he was named associate professor. He retired at age 76, and died on February 20, 1990, aged 77.
References
Kata Kunci Pencarian:
Harry Klinefelter | American physician | Britannica
Harry Klinefelter - Alchetron, The Free Social Encyclopedia
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How to pronounce harry klinefelter | HowToPronounce.com
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