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Kodeina atau kodein (bahasa Inggris: codeine, methylmorphine) ialah asam opiat alkaloid yang dijumpai di dalam candu dalam konsentrasi antara 0,7% dan 2,5%. Kebanyakan kodein yang digunakan di Amerika Serikat diproses dari morfin melalui proses metilasi.
Kodein yang terkonsumsi akan teraktivasi oleh enzim CYP2D6 di dalam hati menjadi morfin, sebelum mengalami proses glukuronidasi, sebuah mekanisme detoksifikasi bagi xenobiotik.
Bagaimanapun, morfin tersebut tidak dapat digunakan, mengingat 90% kodein yang ada akan dieliminasi dalam usus halus sebelum berhasil memasuki peredaran darah. Oleh karena itu, kodein seolah-olah tidak berpengaruh atas penggunanya, namun efek samping seperti analgesia, sedasi, dan penekanan pernapasan masih terasa.
Kodein digunakan sebagai pereda nyeri ringan. Kodein dibuat dalam bentuk pil atau cairan dan bisa diambil baik secara sendirian atau gabungan dengan kafeina, aspirin, asetaminofen, atau ibuprofen. Kodein sangat berperan untuk meredakan batuk.
Seperti semua jenis opioid, penggunaan kodein terus-menerus dapat mengakibatkan ketergantungan secara fisik dan psikologi. Sebuah kelompok yang bernama Codeine Free Diarsipkan 2010-05-01 di Wayback Machine. didirikan untuk membantu mereka yang mengalami ketergantungan pada kodein.
Kodein merupakan obat yang paling banyak digunakan dalam perawatan kesehatan.




Rujukan






Lihat pula


Jenis-jenis obat analgesik yang lain ialah:

Parasetamol
Aspirin




Pranala luar


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Kodein | PDF

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KODEIN – Free Font(s) on Behance

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Daftar Isi

• Codeine - Wikipedia
• Codeine Uses, Dosage, Side Effects & Warnings - Drugs.com
• Codeine: 7 things you should know - Drugs.com
• Codeine - StatPearls - NCBI Bookshelf - National Center for ...
• Codeine - Uses, Side Effects, and More - WebMD
• Codeine Tablets: Uses & Side Effects - Cleveland Clinic
• Codeine: Uses, Interactions, Mechanism of Action | DrugBank ...

Codeine - Wikipedia

Codeine is used to treat mild to moderate pain. [4] It is commonly used to treat post-surgical dental pain. [13]Weak evidence indicates that it is useful in cancer pain, but it may have increased adverse effects, especially constipation, compared to other opioids. [14]

Codeine Uses, Dosage, Side Effects & Warnings - Drugs.com

Aug 23, 2023 · Codeine is a opioid pain medicine used to treat mild to moderate pain. Includes codeine side effects, interactions and indications.

Codeine: 7 things you should know - Drugs.com

Jul 5, 2023 · Quick easy-to-read overview of codeine. Includes: how it works, upsides, downsides, bottom line, tips, response and effectiveness.

Codeine - StatPearls - NCBI Bookshelf - National Center for ...

Feb 28, 2024 · Codeine is a member of the opioid class of medications and is used to manage pain. Codeine is also used to treat cough. For mild-to-moderate pain, codeine is often used as a combined medication with acetaminophen or with an NSAID like ibuprofen. The drug is often available as a combination product with promethazine or an NSAID like salicylic acid for cough …

Codeine - Uses, Side Effects, and More - WebMD

Oct 21, 2024 · Find patient medical information for Codeine on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

Codeine Tablets: Uses & Side Effects - Cleveland Clinic

Codeine tablets are an opioid medication that treats pain. A healthcare provider will prescribe this medication to you if other medications don’t work.

Codeine: Uses, Interactions, Mechanism of Action | DrugBank ...

Generic Name Codeine DrugBank Accession Number DB00318 Background. The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.