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Beta-Lactamase Inhibitors - StatPearls - NCBI Bookshelf
β-Lactamase inhibitor - Wikipedia
List of Beta-lactamase inhibitors - Drugs.com
β-Lactams and β-Lactamase Inhibitors: An Overview - PMC
List of Penicillins/beta-lactamase inhibitors - Drugs.com
List of Cephalosporins/beta-lactamase inhibitors - Drugs.com
Beta-Lactamase Inhibitors: Mechanisms, Types, and Resistance
β-lactam/β-lactamase inhibitor combinations: an update - PMC
Beta-Lactamase Inhibitors - PubMed
Old and New Beta-Lactamase Inhibitors: Molecular Structure, …

Beta-Lactamase Inhibitors - StatPearls - NCBI Bookshelf

Sep 26, 2022 · Beta-lactamase inhibitors are drugs that are co-administered with beta-lactam antimicrobials to prevent antimicrobial resistance by inhibiting serine beta-lactamases, which are enzymes that inactivate the beta-lactam ring, which is a common chemical structure to all beta-lactam antimicrobials.

β-Lactamase inhibitor - Wikipedia

The most important use of beta-lactamase inhibitors is in the treatment of infections known or believed to be caused by gram-negative bacteria, as beta-lactamase production is an important contributor to beta-lactam resistance in these pathogens.

List of Beta-lactamase inhibitors - Drugs.com

Beta-lactamase inhibitors are a class of medicine that block the activity of beta-lactamase enzymes (also called beta-lactamases), preventing the degradation of beta-lactam antibiotics. They tend to have little antibiotic activity on their own.

β-Lactams and β-Lactamase Inhibitors: An Overview - PMC

The newest effort to circumvent resistance is the development of novel broad-spectrum β-lactamase inhibitors that work against many problematic β-lactamases, including cephalosporinases and serine-based carbapenemases, which severely limit therapeutic options.

List of Penicillins/beta-lactamase inhibitors - Drugs.com

Compare penicillins/beta-lactamase inhibitors. View important safety information, ratings, user reviews, popularity and more.

List of Cephalosporins/beta-lactamase inhibitors - Drugs.com

Beta-lactamase inhibitors block the activity of beta-lactamase enzymes. Some species of bacteria produce beta-lactamase enzymes, which cleave the beta-lactam group in antibiotics, such as cephalosporins, that have a beta-lactam ring in their structure.

Beta-Lactamase Inhibitors: Mechanisms, Types, and Resistance

Oct 19, 2024 · Beta-lactamase inhibitors target the enzymes that compromise the effectiveness of beta-lactam antibiotics. Structurally similar to beta-lactam antibiotics, these inhibitors bind to the active site of beta-lactamase enzymes, typically resulting in irreversible inactivation.

β-lactam/β-lactamase inhibitor combinations: an update - PMC

The present review provides an overview of recent FDA-approved β-lactam/β-lactamase inhibitor combinations as well as an update on research efforts aimed at the discovery and development of novel β-lactamase inhibitors.

Beta-Lactamase Inhibitors - PubMed

Beta-lactamase inhibitors are co-administered with beta-lactam antimicrobials to prevent antimicrobial resistance. They do this by inhibiting serine beta-lactamases, enzymes that inactivate the beta-lactam ring which are a common chemical structure to …

Old and New Beta-Lactamase Inhibitors: Molecular Structure, …

The present review provides the status and knowledge concerning current β-lactamase inhibitors and an update on research efforts to identify and develop new and more efficient β-lactamase inhibitors.