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Mostafa A. El-Sayed (Arabic: مصطفى السيد) is an Egyptian-American physical chemist, nanoscience researcher, member of the National Academy of Sciences and US National Medal of Science laureate. He is known for the spectroscopy rule named after him, the El-Sayed rule.
Early life and academic career
El-Sayed was born in Zifta, Egypt and spent his early life in Cairo. He earned his B.Sc. in chemistry from Ain Shams University Faculty of Science, Cairo in 1953. El-Sayed earned his doctoral degree in chemistry from Florida State University working with Michael Kasha, the last student of the legendary G. N. Lewis. While attending graduate school he met and married Janice Jones, his wife of 48 years. He spent time as a post-doctoral researcher at Harvard University, Yale University and the California Institute of Technology before joining the faculty of the University of California at Los Angeles in 1961. In 1994, he retired from UCLA and accepted the position of Julius Brown Chair and Regents Professor of Chemistry and Biochemistry at the Georgia Institute of Technology. He led the Laser Dynamics Lab there until his full retirement in 2020.
El-Sayed is a former editor-in-chief of the Journal of Physical Chemistry (1980–2004).
Research
El-Sayed's research interests include the use of steady-state and ultra fast laser spectroscopy to understand relaxation, transport and conversion of energy in molecules, in solids, in photosynthetic systems, semiconductor quantum dots and metal nanostructures. The El-Sayed group has also been involved in the development of new techniques such as magnetophotonic selection, picosecond Raman spectroscopy and phosphorescence microwave double resonance spectroscopy. A major focus of his lab is currently on the optical and chemical properties of noble metal nanoparticles and their applications in nanocatalysis, nanophotonics and nanomedicine. His lab is known for the development of the gold nanorod technology. As of 2021, El-Sayed has produced over 1200 publications in refereed journals in the areas of spectroscopy, molecular dynamics and nanoscience, with over 130,000 citations.
Honors
For his work in the area of applying laser spectroscopic techniques to study of properties and behavior on the nanoscale, El-Sayed was elected to the National Academy of Sciences in 1980. In 1989 he received the Tolman Award, and in 2002, he won the Irving Langmuir Award in Chemical Physics. He has been the recipient of the 1990 King Faisal International Prize ("Arabian Nobel Prize") in Sciences, Georgia Tech's highest award, "The Class of 1943 Distinguished Professor", an honorary doctorate of philosophy from the Hebrew University, and several other awards including some from the different American Chemical Society local sections. He was a Sherman Fairchild Distinguished Scholar at the California Institute of Technology and an Alexander von Humboldt Senior U.S. Scientist Awardee. He served as editor-in-chief of the Journal of Physical Chemistry from 1980 to 2004 and has also served as the U.S. editor of the International Reviews in Physical Chemistry. He is a Fellow of the American Academy of Arts and Sciences, a member of the American Physical Society, the American Association for the Advancement of Science and the Third World Academy of Science. Mostafa El-Sayed was awarded the 2007 US National Medal of Science "for his seminal and creative contributions to our understanding of the electronic and optical properties of nanomaterials and to their applications in nanocatalysis and nanomedicine, for his humanitarian efforts of exchange among countries and for his role in developing the scientific leadership of tomorrow." Mostafa was also announced to be the recipient of the 2009 Ahmed Zewail prize in molecular sciences. In 2011, he was listed #17 in Thomson-Reuters listing of the Top Chemists of the Past Decade. Professor El-Sayed also received the 2016 Priestley Medal, the American Chemical Society’s highest honor, for his decades-long contributions to chemistry.
The El-Sayed rule
The rate of intersystem crossing is relatively large if the radiationless transition involves a change of orbital type.
This rule pertains to phosphorescence and similar phenomena. Electrons vibrate and resonate around molecules in different modes (electronic state), usually depending on the energy of the system of electrons. This law states that constant-energy flipping between two electronic states happens more readily when the vibrations of the electrons are preserved during the flip: any change in the spin of an electron is compensated by a change in its orbital motion (spin-orbit coupling).
Intersystem crossing (ISC) is a photophysical process involving an isoenergetic radiationless transition between two electronic states having different multiplicities. It often results in a vibrationally excited molecular entity in the lower electronic state, which then usually decays to its lowest molecular vibrational level. ISC is forbidden by rules of conservation of angular momentum. As a consequence, ISC generally occurs on very long time scales. However, the El-Sayed rule states that the rate of intersystem crossing, e.g. from the lowest singlet state to the triplet manifold, is relatively large if the radiationless transition involves a change of molecular orbital type. For example, a (π,π*) singlet could transition to a (n,π*) triplet state, but not to a (π,π*) triplet state and vice versa. Formulated by El-Sayed in the 1960s, this rule found in most photochemistry textbooks as well as the IUPAC Gold Book. The rule is useful in understanding phosphorescence, vibrational relaxation, intersystem crossing, internal conversion and lifetimes of excited states in molecules.
Notes
References
El-Sayed, M.A., Acc. Chem. Res. 1968,1,8.
Lower, S.K.; El-Sayed, M.A., Chem. Rev. 1966,66,199
Mostafa Amr El-Sayed (8 May 1933 – Egyptian-American, b. Zifta, Egypt)
Biographical References: McMurray, Emily J. (ed.), Notable Twientieth-Century Scientists, Gale Research, Inc.: New York, 1995.
External links
Faculty web page at Georgia Tech
Laser Dynamics Lab at Georgia Tech
President Bush to laud Georgia Tech’s Mostafa El-Sayed
Mostafa El-Sayed praised for contributions to nanotechnology
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Mostafa El-Sayed - Wikipedia
Mostafa A. El-Sayed (Arabic: مصطفى السيد) is an Egyptian-American physical chemist, nanoscience researcher, member of the National Academy of Sciences and US National Medal of Science laureate.
Mostafa El-Sayed | School of Chemistry & Biochemistry
Professor El-Sayed's research group is housed in the Laser Dynamics Laboratory (LDL). LDL (https://ldl.gatech.edu) houses the most recent lasers and laser spectroscopic equipment for time-resolved studies in the femto-to-millisecond time scale.
Mostafa A. El-Sayed - Google Scholar
Julius Brown Chair and Regents Professor,Department of Chemistry and Biochemistry, Georgia Tech. Why gold nanoparticles are more precious than pretty gold: noble metal surface plasmon resonance and...
Mostafa El-Sayed - American University of Beirut
Mostafa El-Sayed is an internationally renowned Egyptian-American physical chemist and a leading nanoscience researcher. A long time teacher, Professor El-Sayed has recently turned his attention to developing new approaches to cancer treatment.
Dr.Mostafa A. El-Sayed - Egypt Cancer Network
El-Sayed has supervised the research of over 70 PhD students, 35 postdoctoral fellows and 20 visiting professors, several of whom hold key positions in the scientific community. Dr. Mostafa El Sayed’s son, Dr. Ivan El-Sayed, the Professor of Tumor Surgery at the University of California, took part in applying these outcomes on cancerous cells ...
Mostafa El-Sayed - Regents' Professor Emeritus - LinkedIn
Regents' Professor Emeritus, School of Chemistry and Biochemistry, Georgia Institute of Technology · Experience: Georgia Institute of Technology · Education: Florida State University · Location:...
Mostafa A. El-Sayed - National Science and Technology Medals ...
Born and raised in Egypt, El-Sayed was the first Arab-American to be awarded the National Medal of Science. He is a tireless advocate of international scientific collaboration and regularly brings groups of American nanotechnology experts to his native country to share and learn from Egyptian scientists.