paola leone

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      Paola Leone is an Italian researcher of Canavan disease, a leukodystrophy.
      Leone was born and raised in Cagliari, Italy. She received her undergraduate and graduate training in Italy, followed by post-doctoral studies in Montreal and Yale University in New Haven, CT. She holds a doctorate degree in Neuroscience from the University of Padua. Her work on Canavan disease started at Yale, where she collaborated with other early pioneers in gene therapy. She left Yale in 1998 to join the (now defunct) Cell & Gene Therapy Center at Thomas Jefferson University in Philadelphia. She directs The Cell & Gene Therapy Center at the University of Medicine and Dentistry of New Jersey.
      Recently, she has been funded by NIH-NINDS and Jacob's Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including the Canavan mouse model. She is generating pre-clinical data using human Embryonic-Derived-Oligodendrocyte Stem Cells provided by Geron Corporation (CA). These studies will provide a foundation for a targeted and comprehensive analysis of the potential of a cell-based therapy for Canavan Disease.


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    Faculty and Staff | Rowan Research | Rowan ... - Rowan University

    Dr. Paola Leone is a Professor of Cell Biology. She directs all research activities at RowanSOM and the affiliated centers. Her research interests have included in vivo neurochemistry of …

    Paola Leone - Wikipedia

    Paola Leone is an Italian researcher of Canavan disease, a leukodystrophy. Leone was born and raised in Cagliari, Italy. She received her undergraduate and graduate training in Italy, followed …

    Cell and Gene Therapy Center | Rowan Research - Rowan …

    Our laboratory, under the direction of Dr. Paola Leone, studies pediatric white matter diseases and characterizes mechanisms to repair white matter with the goal to prevent and treat …

    Our Team — The Canavan Research Foundation

    Dr. Paola Leone, Ph.D. - Professor of Cell Biology and Director of the Cell & Gene Therapy Center at the Rowan University School of Osteopathic Medicine. Following post-doctoral …

    Contact Us | Rowan Research | Rowan University

    Paola Leone Director of Cell and Gene Therapy Center Professor, Department of Cell Biology & Neuroscience Rowan University School of Osteopathic Medicine 42 E Laurel Road, Rowan …

    Paola Leone - Rowan University

    Dive into the research topics where Paola Leone is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    Paola Leone - Cherry Hill, New Jersey, United States ...

    Location: Cherry Hill · 500+ connections on LinkedIn. View Paola Leone’s profile on LinkedIn, a professional community of 1 billion members.

    Research | Cure Caravan Fund | New York

    Paola Leone, Ph.D (Professor of Cell Biology & Director of the Cell and Gene Therapy Center at Rowan School of Osteopathic Medicine) has devoted her entire career to Canavan disease …

    Rowan SOM researcher meets pope - CourierPostOnline.com

    Dec 14, 2015 · Leone and her fellow researchers have since developed a novel gene therapy using a virus to target the affected brain cells of young patients.

    Paola Leone - Postdoctoral Researcher - Icahn School of ...

    View Paola Leone’s profile on LinkedIn, a professional community of 1 billion members. Postdoctoral fellow at Icahn School of Medicine at Mount Sinai, Department of Neurology · …