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- Placental site trophoblastic tumor
- Trophoblastic neoplasm
- Gestational trophoblastic disease
- Ovary
- Placental site nodule
- International Classification of Diseases for Oncology
- Gestational choriocarcinoma
- Trophoblast
- Intermediate trophoblast
- Seminoma
- Placental site trophoblastic tumor - Wikipedia
- Placental site trophoblastic tumour - PubMed
- Diagnosis and treatment of placental site trophoblastic tumor
- Placental site trophoblastic tumour: the rarest subtype of …
- Placental site trophoblastic tumor - Radiopaedia.org
- A Review on the Pathogenesis and Clinical Management of Placental Site ...
- Placental site trophoblastic tumour and ... - Cancer Research UK
- Gestational Trophoblastic Disease Treatment - NCI
- Placental Site Trophoblastic Tumors and Epithelioid Trophoblastic ...
- Gestational Trophoblastic Disease: Symptoms & Treatment - Cleveland Clinic
Parasite (2019)
Deranged (2012)
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A placental site trophoblastic tumor is a form of gestational trophoblastic disease, which is thought to arise from the intermediate trophoblast.
The tumor may secrete human placental lactogen, and result in a false-positive pregnancy test.
A placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy (5%). Compared to choriocarcinoma or invasive mole, hemorrhage is less conspicuous and serum β-HCG level is low, making early diagnosis difficult.
Diagnosis
Immunohistochemistry often shows positive staining for hPL, keratin, Mel-CAM, and EGFR., This immunohistochemical profile, particularly the strong positivity for hPL and Mel-CAM, along with the negative or focal staining for β-hCG and p63, helps distinguish PSTT from other types of gestational trophoblastic neoplasia such as choriocarcinoma and epithelioid trophoblastic tumour.
Treatment
If the causative pregnancy occurred less than 48 months prior to the tumor's diagnosis, the tumor can be removed via a hysterectomy without the need for adjunct systemic therapy. However, if more than 48 months have passed, or if the tumor is of stage II or higher, adjunct systemic therapy should be offered in the form of aggressive platinum-based chemotherapy. When possible, residual masses should be removed following treatment to insure against recurrence.
Prognosis
10–20% of cases metastasize leading to death.
References
External links
Kata Kunci Pencarian:
Placental Site Trophoblastic Tumor and Related Lesions of | PDF ...
Trophoblastic Tumor, Placental Site | Semantic Scholar
Trophoblastic Tumor, Placental Site | Semantic Scholar
Trophoblastic Tumor, Placental Site | Semantic Scholar
Placental site trophoblastic tumor. Mono- or multinucleated ...
(PDF) Placental site trophoblastic tumor
A Rare Case of Placental Site Trophoblastic Tumor | Biores Scientia
Placental site trophoblastic tumor (left part of the pictures ...
Placental site trophoblastic tumor (left part of the pictures ...
Placental site trophoblastic tumor (left part of the pictures ...
(PDF) Placental Site Trophoblastic Tumor: A case report
Trophoblastic tumor, placental site; Placental-Site Trophoblastic Tumor
placental site trophoblastic tumor
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Placental site trophoblastic tumor - Wikipedia
A placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy (5%).
Placental site trophoblastic tumour - PubMed
Placental site trophoblastic tumour (PSTT) is a very rare and unique form of gestational trophoblastic disease (GTD). This tumour represents a neoplastic transformation of intermediate trophoblastic cells that normally play a critical role in implantation.
Diagnosis and treatment of placental site trophoblastic tumor
Placental site trophoblastic tumor (PSTT) refers to a special type of gestational trophoblastic neoplasm (GTN) that originates from placental implantation site. Its incidence is approximately 1 per 100,000 pregnancies, about 1-2% of all the GTNs, mortality rate is 25% [ 1 ], About 200 cases of PSTT have been reported all over the world [ 2 ].
Placental site trophoblastic tumour: the rarest subtype of …
Placental site trophoblastic tumour (PSTT) is a very rare form of gestational trophoblastic disease that grows slowly, secretes low levels of beta-subunit of human chorionic gonadotropin (β-hCG), presents late-onset metastatic potential and is resistant to several chemotherapy regimens.
Placental site trophoblastic tumor - Radiopaedia.org
Apr 27, 2024 · A placental site trophoblastic tumor is a neoplastic transformation of intermediate trophoblastic cells with varied gross features, such as a polyploid enlarged mass or diffuse microscopic findings. Many tumors can infiltrate the myometrium and extend to the serosa.
A Review on the Pathogenesis and Clinical Management of Placental Site ...
Placental site trophoblastic tumor (PSTT) is a rare type of gestational trophoblastic disease originating from the intermediate trophoblast. Compared with hydatidiform mole, invasive hydatidiform mole and choriocarcinoma, the diagnosis of PSTT is ...
Placental site trophoblastic tumour and ... - Cancer Research UK
Placental site trophoblastic tumours (PSTTs) and epithelioid trophoblastic tumours (ETTs) happen after pregnancy. They are extremely rare and are slow growing.
Gestational Trophoblastic Disease Treatment - NCI
Feb 25, 2022 · A placental-site trophoblastic tumor (PSTT) is a rare type of gestational trophoblastic neoplasia that forms where the placenta attaches to the uterus. The tumor forms from trophoblast cells and spreads into the muscle of the uterus and into blood vessels.
Placental Site Trophoblastic Tumors and Epithelioid Trophoblastic ...
Sep 24, 2024 · Placental site trophoblastic disease (PSTT) and epithelioid trophoblastic tumor (ETT) are the rarest forms of gestational trophoblastic neoplasia (GTN) with unique clinical features and treatment considerations. Unlike other GTN, human chorionic gonadotropin (hCG) is minimally, if at all, elevated.
Gestational Trophoblastic Disease: Symptoms & Treatment - Cleveland Clinic
Jun 14, 2022 · A placental-site trophoblastic tumor (PSTT) is an extremely rare type of GTD that forms where the placenta attaches to your uterus. A PSTT grows very slowly, and symptoms may appear years after pregnancy.