terpenoid

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      The terpenoids, also known as isoprenoids, are a class of naturally occurring organic chemicals derived from the 5-carbon compound isoprene and its derivatives called terpenes, diterpenes, etc. While sometimes used interchangeably with "terpenes", terpenoids contain additional functional groups, usually containing oxygen. When combined with the hydrocarbon terpenes, terpenoids comprise about 80,000 compounds. They are the largest class of plant secondary metabolites, representing about 60% of known natural products. Many terpenoids have substantial pharmacological bioactivity and are therefore of interest to medicinal chemists.
      Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, ginkgolide and bilobalide found in Ginkgo biloba and the cannabinoids found in cannabis. The provitamin beta carotene is a terpene derivative called a carotenoid.
      The steroids and sterols in animals are biologically produced from terpenoid precursors. Sometimes terpenoids are added to proteins, e.g., to enhance their attachment to the cell membrane; this is known as isoprenylation. Terpenoids play a role in plant defense as prophylaxis against pathogens and attractants for the predators of herbivores.


      Structure and classification


      Terpenoids are modified terpenes, wherein methyl groups have been moved or removed, or oxygen atoms added. Some authors use the term "terpene" more broadly, to include the terpenoids. Just like terpenes, the terpenoids can be classified according to the number of isoprene units that comprise the parent terpene:

      Terpenoids can also be classified according to the type and number of cyclic structures they contain: linear, acyclic, monocyclic, bicyclic, tricyclic, tetracyclic, pentacyclic, or macrocyclic. The Salkowski test can be used to identify the presence of terpenoids.

      Selected terpenoids






























      Biosynthesis



      Terpenoids, at least those containing an alcohol functional group, often arise by hydrolysis of carbocationic intermediates produced from geranyl pyrophosphate. Analogously hydrolysis of intermediates from farnesyl pyrophosphate gives sesquiterpenoids, and hydrolysis of intermediates from geranylgeranyl pyrophosphate gives diterpenoids, etc.


      Impact on aerosols


      In air, terpenoids are converted into various species, such as aldehydes, hydroperoxides, organic nitrates, and epoxides by short-lived free radicals (like the hydroxyl radical) and to a lesser extent by ozone. These new species can dissolve into water droplets and contribute to aerosol and haze formation. Secondary organic aerosols formed from this pathway may have atmospheric impacts.
      As an example the Blue Ridge Mountains in the U.S. and Blue Mountains of New South Wales in Australia are noted for having a bluish color when seen from a distance. Trees put the "blue" in Blue Ridge, from their terpenoids released into the atmosphere.


      See also


      List of antioxidants in food
      List of phytochemicals in food
      Nutrition
      Phytochemistry
      Secondary metabolites


      References




      External links


      IUPAC definition of terpenoids

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    Terpenoid - wikidoc

    Terpenoid - wikidoc

    Terpenoid - wikidoc

    SOLUTION: Terpenoid - Studypool

    SOLUTION: Terpenoid - Studypool

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    Terpenoid Profiles and Potency: Types and Testing | PureLabs OKC

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    Biosynthetic pathways for terpenoid production. | Download Scientific ...

    Figure 1 from Terpenoid biomaterials. | Semantic Scholar

    Figure 1 from Terpenoid biomaterials. | Semantic Scholar

    Camphor Molecule. it is Terpenoid and a Cyclic Ketone. Molecular Model ...

    Camphor Molecule. it is Terpenoid and a Cyclic Ketone. Molecular Model ...

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    Chemical structures of terpenoid alkaloids comprising the... | Download ...

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    3D image of tauremizin skeletal formula - molecular chemical structure ...

    Figure 1 from Terpenoid metabolism. | Semantic Scholar

    Figure 1 from Terpenoid metabolism. | Semantic Scholar

    Terpenoid products of three structural classes, which are accumulated ...

    Terpenoid products of three structural classes, which are accumulated ...

    Outline of the Basic Pathways of Terpenoid Metabolism, Including the ...

    Outline of the Basic Pathways of Terpenoid Metabolism, Including the ...