• Source: 1-Phenylethylamine

1-Phenylethylamine is the organic compound with the formula C6H5CH(NH2)CH3. This primary amine is a colorless liquid is often used in chiral resolutions. Like benzylamine, it is relatively basic and forms stable ammonium salts and imines.




Preparation and optical resolution


1-Phenylethylamine may be prepared by the reductive amination of acetophenone:

C6H5C(O)CH3 + NH3 + H2 → C6H5CH(NH2)CH3 + H2O
The Leuckart reaction, using ammonium formate, is another method for this transformation.
L-malic acid is used to resolve 1-Phenylethylamine, a versatile resolving agent in its own right. The dextrorotatory enantiomer crystallizes with the malate, leaving the levorotatory form in solution.




See also


2-Phenylethylamine




References

Kata Kunci Pencarian:

• Psikotropika
• Pecinta cokelat
• Psilosibin
• Fenilpropanolamina
• Rasagilin
• Nikel Raney
• 1-Phenylethylamine
• Phenethylamine
• Benzylamine
• 2-Methylmethcathinone
• (S)-N-acetyl-1-phenylethylamine hydrolase
• C8H11N
• Chiral resolution
• Reductive amination
• Synthetic drug
• Amphetamine