- Source: 2-Cyanoguanidine
2-Cyanoguanidine is a nitrile derived from guanidine. It is a dimer of cyanamide, from which it can be prepared. 2-Cyanoguanidine is a colourless solid that is soluble in water, acetone, and alcohol, but not nonpolar organic solvents.
Production and use
2-Cyanoguanidine is produced by treating cyanamide with base. It is produced in soil by decomposition of cyanamide. A variety of useful compounds are produced from 2-cyanoguanidine, guanidines and melamine. For example, acetoguanamine and benzoguanamine are prepared by condensation of cyanoguanidine with the nitrile:
(H2N)2C=NCN + RCN → (CNH2)2(CR)N3
Cyanoguanidine is also used as a slow fertilizer. Formerly, it was used as a fuel in some explosives. It is used in the adhesive industry as a curing agent for epoxy resins.
Chemistry
Two tautomeric forms exist, differing in the protonation and bonding of the nitrogen to which the nitrile group is attached.
2-Cyanoguanidine can also exist in a zwitterionic form via a formal acid–base reaction among the nitrogens.
Loss of ammonia (NH3) from the zwitterionic form, followed by deprotonation of the remaining central nitrogen atom, gives the dicyanamide anion, [N(CN)2]−.
Drugs List
2-Cyanoguanidine finds use in the synthesis of the following list of agents:
Amanozine
Azapropazone
Buformin
Chlorazanil
Chlorproguanil
Clociguanil
Cloguanamil
Cloquanamil
Cycloguanil
Dametralast
Diallylmelamine (DAM)
Guanazole
Irsogladine
Metformin
Methylphenobarbital
Moroxydine
Oxonazine
Phenformin
Phenylbiguanide
NSC-127755
Triazinate
References
External links
International Chemical Safety Card 0650
OECD document Archived 2017-05-17 at the Wayback Machine
Entry at chemicalland21.com
Kata Kunci Pencarian:
- 2-Cyanoguanidine
- DCD
- Dicyanamide
- Metformin
- Carbon compounds
- Cyanamide
- Fonterra
- C2H4N4
- Dithiobiuret
- Food safety in New Zealand
