• Source: 4-Fluorobenzoic acid

4-Fluorobenzoic acid (p-fluorobenzoic acid) is an organic compound with the formula C7H5FO2. This colourless solid is a derivative of benzoic acid carboxylic acid. It is a synthetic intermediate.




Preparation


4-Fluorobenzoic acid is commercially available. It may be prepared via the Schiemann reaction, in which a 4-aminobenzoic acid, protected as the ethyl ester, is diazotised and then fluoride introduced using tetrafluoroborate. Hydrolysis of the ester converts it back to the free acid.

4-Fluorobenzoic acid has been observed to form by the aerobic biotransformation of 4-fluorocinnamic acid.




See also


2-Fluorobenzoic acid, the ortho isomer
3-Fluorobenzoic acid, the meta isomer




References

Kata Kunci Pencarian:

• Kamus rumus kimia
• 4-Fluorobenzoic acid
• Fluorobenzoic acid
• 3-Fluorobenzoic acid
• 2-Fluorobenzoic acid
• Balz–Schiemann reaction
• 3-(p-Fluorobenzoyloxy)tropane
• Acoramidis
• C7H5FO2
• Glossary of chemical formulae