- Source: 5-Fluoro-DMT
5-Fluoro-N,N-dimethyltryptamine (5-fluoro-DMT, 5F-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-MeO-DMT. It produces a robust head-twitch response in mice, and hence is a putative serotonergic psychedelic. Fluorination of psychedelic tryptamines either reduces or has little effect on 5-HT2A/C receptor affinity or intrinsic activity, although 6-fluoro-DET is inactive as a psychedelic despite acting as a 5-HT2A agonist (cf. lisuride), while 4-fluoro-5-methoxy-DMT is a much stronger agonist at 5-HT1A than 5-HT2A.
See also
5-Fluoro-AMT
5-Fluoro-DET
5-Fluoro-MET
6-fluoro-AMT
6-Fluoro-DMT
4-fluoro-5-methoxy-DMT
6-Fluoro-DET(6-Fluoro-DET)
O-4310
It's worth noting that GR-159897 is based on the same structure.
References
Kata Kunci Pencarian:
- 5-Fluoro-DMT
- 5-Chloro-DMT
- 5-Bromo-DMT
- 6-Fluoro-DMT
- 5-Fluoro-AET
- 4-Fluoro-5-methoxy-DMT
- 5-TFM-DMT
- 5-TFMO-DMT
- 5-Fluoro-MET
- 6-MeO-DMT