• Source: Cathepsin A

Cathepsin A is an enzyme that is classified both as a cathepsin and a carboxypeptidase. In humans, it is encoded by the CTSA gene.




Function


This gene encodes a glycoprotein that associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high-molecular-weight multimers. The formation of this complex provides a protective role for stability and activity. It is protective for β-galactosidase and neuraminidase.




Clinical significance


Deficiencies in this gene are linked to multiple forms of galactosialidosis.




Interactions


Cathepsin A has been shown to interact with NEU1.




References






Further reading






External links


Cathepsin+A at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• Sisteina protease
• Sofosbuvir
• Displasia pangkal paha (anjing)
• Perangkap ekstraseluler neutrofil
• Kanker payudara
• Cathepsin
• Cathepsin A
• Cathepsin B
• Osteoclast
• Cathepsin L
• Cathepsin S
• Cathepsin K
• Cathepsin L1
• Cathepsin C
• Cathepsin E