• Source: CBX3

Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans.
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.




Interactions


CBX3 has been shown to interact with PIM1, Ki-67, Lamin B receptor, CBX5 and CBX1.




See also


Heterochromatin protein 1




References






Further reading






External links


CBX3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human CBX3 genome location and CBX3 gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/1
• CBX3
• Ki-67 (protein)
• List of human protein-coding genes 1
• Stress granule
• Heterochromatin protein 1
• BAP1
• SUHW4
• Lamin B receptor
• CBX1
• CBX5 (gene)