• Source: CLK1

Dual specificity protein kinase CLK1 is an enzyme that in humans is encoded by the CLK1 gene.




Function


This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the cell nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine-rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.




Interactions


CLK1 has been shown to interact with ASF/SF2.




References






External links


Human CLK1 genome location and CLK1 gene details page in the UCSC Genome Browser.




Further reading

• Source: CLK-1

CLK-1, clk1, or variation, may refer to:

USS Norfolk (CLK-1), post-World War II light cruiser reclassified as a destroyer leader (DL)
clk-1 (gene), the clock-1 gene for ubiquinone biosynthesis encoding DMQ hydroxylase
CLK1 (protein), the human enzyme dual specificity protein kinase CLK1, encoded by the CLK1 gene




See also



All pages with titles containing CLK-1
All pages with titles containing CLK1
CLK (disambiguation)

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