• Source: CLK2

Dual specificity protein kinase CLK2 is an enzyme that in humans is encoded by the CLK2 gene.




Function


This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine/arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.




References






External links


Human CLK2 genome location and CLK2 gene details page in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: P49760 (Dual specificity protein kinase CLK2) at the PDBe-KB.




Further reading

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