• Source: Glycosyl

In organic chemistry, a glycosyl group is a univalent free radical or substituent structure obtained by removing the hydroxyl (−OH) group from the hemiacetal (−CH(OH)O−) group found in the cyclic form of a monosaccharide and, by extension, of a lower oligosaccharide. Glycosyl groups are exchanged during glycosylation from the glycosyl donor, the electrophile, to the glycosyl acceptor, the nucleophile. The outcome of the glycosylation reaction is largely dependent on the reactivity of each partner. Glycosyl also reacts with inorganic acids, such as phosphoric acid, forming an ester such as glucose 1-phosphate.




Examples


In cellulose, glycosyl groups link together 1,4-β-D-glucosyl units to form chains of (1,4-β-D-glucosyl)n.
Other examples include ribityl in 6,7-Dimethyl-8-ribityllumazine, and glycosylamines.




Alternative substituent groups



Instead of the hemiacetal hydroxyl group, a hydrogen atom can be removed to form a substituent, for example the hydrogen from the C3 hydroxyl of a glucose molecule. Then the substituent is called D-glucopyranos-3-O-yl as it appears in the name of the drug Mifamurtide.
Recent detection of the Au3+ in living organism was possible through the use of C-glycosyl pyrene, where its permeability through cell membrane and fluorescence properties were used to detect Au3+.




See also


Acyl group




References

Kata Kunci Pencarian:

• Alfa-amilase
• Beta-amilase
• Glikosiltransferase
• Glukoamilase
• Metaloproteinase matriks
• N-Bromosuksinimida
• Glycosyl
• Glycosyl donor
• Chemical glycosylation
• Glycosyltransferase
• Glycosyl acceptor
• Glycoside hydrolase
• Glycosylphosphatidylinositol
• Enzyme catalysis
• Koenigs–Knorr reaction
• Glycosylamine