- Source: Integrin beta 3
3/info/integrin" target="_blank">Integrin 3/info/beta" target="_blank">beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes.
Structure and function
The ITGB3 protein product is the 3/info/integrin" target="_blank">integrin 3/info/beta" target="_blank">beta chain 3/info/beta" target="_blank">beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a 3/info/beta" target="_blank">beta chain. A given chain may combine with multiple partners resulting in different integrins. 3/info/integrin" target="_blank">Integrin 3/info/beta" target="_blank">beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated signaling.
Role in endometriosis
Defectively expressed β3 3/info/integrin" target="_blank">integrin subunit has been correlated with presence of endometriosis, and has been suggested as a putative marker of this condition.
Interactions
CD61 has been shown to interact with PTK2, ITGB3BP, TLN1 and CIB1.
See also
Glycoprotein IIb/IIIa
References
Further reading
External links
CD61+Antigens at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
ITGB3 Info with links in the Cell Migration Gateway Archived 2014-12-11 at the Wayback Machine
Human ITGB3 genome location and ITGB3 gene details page in the UCSC Genome Browser.
Kata Kunci Pencarian:
- Transisi epitelial-mesenkimal
- Reseptor terhubung protein G
- Landak laut
- Kanker
- Mangan
- Kanker payudara
- FBN1
- Unsur golongan 7
- Integrin beta 3
- Integrin beta 2
- Integrin beta 1
- Integrin beta 6
- Integrin beta 5
- Alpha-v beta-3
- Integrin
- Glycoprotein IIb/IIIa
- Integrin beta 7
- Integrin beta 8