• Source: LPAR3

Lysophosphatidic acid receptor 3 also known as LPA3 is a protein that in humans is encoded by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).




Function


This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.




Evolution






= Paralogues

=
Source:

LPAR1
LPAR2
S1PR1
S1PR3
S1PR4
S1PR2
S1PR5
CNR1
GPR3
MC5R
GPR6
GPR12
MC4R
CNR2
MC3R
MC1R
MC2R
GPR119




See also


Lysophospholipid receptor




References






Further reading






External links


"Lysophospholipid Receptors: LPA3". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-05.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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