- Source: PEA15
Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene.
PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.
PEA-15 promotes autophagy in glioma cells in a JNK-dependent manner.
Interactions
PEA15 has been shown to interact with:
Caspase 8,
FADD, and
MAPK1,
Phospholipase D1, and
RPS6KA3.