- Source: Pregnane
Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core.
5β-Pregnane is the parent of pregnanediones, pregnanolones, and pregnanediols, and is found largely in urine as a metabolic product of 5β-pregnane compounds.
Pregnanes
Pregnanes are steroid derivatives with carbons present at positions 1 through 21.
Most biologically significant pregnane derivatives fall into one of two groups: pregnenes and pregnadienes. Another class is pregnatrienes.
Pregnenes
Pregnenes have a double bond. Examples include:
Cortisone
Hydrocortisone
Progesterone
Pregnadienes
Pregnadienes have two double bonds. Examples include:
Cyproterone acetate
Danazol
Fluocinonide
See also
5β-Pregnane
Pregnanedione
Pregnanediol
19-Norpregnane
Androstane
Estrane
References
External links
Media related to Pregnane at Wikimedia Commons
Pregnanes at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
PubChem
Diagram at qmul.ac.uk
Definition of Pregnane
Progesterone Chemistry
Progesterone record in European Bioinformatics database