• Source: Solute carrier family 30 member 10

      • Solute carrier family 30 member 10 is a protein that in humans is encoded by the SLC30A10 gene.


      Function


      This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012].


      References




      Further reading



      This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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