- Source: Thorpe reaction
- Selena Gomez
- Metabolisme
- Pregabalin
- Meningitis
- Pembunuhan John F. Kennedy
- J.K. Rowling
- Efek sterik
- Adisi nukleofilik
- Prancis Vichy
- Able Archer 83
- Thorpe reaction
- Dieckmann condensation
- List of organic reactions
- The Testimony of William Thorpe
- Nucleophilic addition
- Nitrile
- Enamine
- Jocelyn Field Thorpe
- Jim Thorpe, Pennsylvania
- Thorpe–Ingold effect
The Thorpe reaction is a chemical reaction described as a self-condensation of aliphatic nitriles catalyzed by base to form enamines. The reaction was discovered by Jocelyn Field Thorpe.
Thorpe–Ziegler reaction
The Thorpe–Ziegler reaction (named after Jocelyn Field Thorpe and Karl Ziegler), or Ziegler method, is the intramolecular modification with a dinitrile as a reactant and a cyclic ketone as the final reaction product after acidic hydrolysis. The reaction is conceptually related to the Dieckmann condensation.
References
External links
Thorpe-Ziegler reaction: 4-Phosphorinanone, 1-phenyl- Organic Syntheses, Coll. Vol. 6, p. 932 (1988); Vol. 53, p. 98 (1973) Link