- Source: Type I keratin
Type I keratins (or Type I cytokeratins) are cytokeratins that constitute the Type I intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. Most of the type I keratins consist of acidic, low molecular weight proteins which in vivo are arranged in pairs of heterotypic Type I and Type II keratin chains, coexpressed during differentiation of simple and stratified epithelial tissues.
Type I keratins are encoded on chromosome 17q and encompasses: K9, K10, K11, K12, K13, K14, K15, K16, K17, K18, K19 and K20. Their molecular weight ranges from 40 kDa (K19) to 64 kDa (K9).
See also
Type II keratin
External links
Type+I+Keratin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Proteopedia page on keratins
Kata Kunci Pencarian:
- Badak jawa
- Belerang
- Metabolisme
- Genetika evolusioner manusia
- Kanker payudara
- Ikan zebra
- Type I keratin
- Type II keratin
- Hair keratin
- Keratin 14
- Keratin 19
- Keratin
- Keratin 6A
- Alpha-keratin
- Keratin 1
- Keratin 10