calcium phosphate

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      The term calcium phosphate refers to a family of materials and minerals containing calcium ions (Ca2+) together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well. Calcium phosphates are white solids of nutritional value and are found in many living organisms, e.g., bone mineral and tooth enamel. In milk, it exists in a colloidal form in micelles bound to casein protein with magnesium, zinc, and citrate–collectively referred to as colloidal calcium phosphate (CCP). Various calcium phosphate minerals, which often are not white owing to impurities, are used in the production of phosphoric acid and fertilizers. Overuse of certain forms of calcium phosphate can lead to nutrient-containing surface runoff and subsequent adverse effects upon receiving waters such as algal blooms and eutrophication (over-enrichment with nutrients and minerals).


      Orthophosphates, di- and monohydrogen phosphates


      These materials contain Ca2+ combined with PO3−4, HPO2−4, or H2PO−4:

      Monocalcium phosphate, E341 (CAS# 7758-23-8 for anhydrous; CAS#10031-30-8 for monohydrate: Ca(H2PO4)2 and Ca(H2PO4)2(H2O)
      Dicalcium phosphate (dibasic calcium phosphate), E341(ii) (CAS# 7757-93-9): CaHPO4 (mineral: monetite), dihydrate CaHPO4(H2O)2 (mineral: brushite) and monohydrate CaHPO4(H2O)
      Tricalcium phosphate (tribasic calcium phosphate or tricalcic phosphate, sometimes referred to as calcium phosphate or calcium orthophosphate, whitlockite), E341(iii) (CAS#7758-87-4): Ca3(PO4)2
      Octacalcium phosphate (CAS# 13767-12-9): Ca8H2(PO4)6·5H2O
      Amorphous calcium phosphate, a glassy precipitate of variable composition that may be present in biological systems.


      Di- and polyphosphates


      These materials contain Ca2+ combined with the polyphosphates, such as P2O4−7 and triphosphate P3O5−10:

      Dicalcium diphosphate (CAS#7790-76-3]: Ca2P2O7
      Calcium triphosphate (CAS# 26158-70-3): Ca5(P3O10)2


      Hydroxy- and oxo-phosphates


      These materials contain other anions in addition to phosphate:

      Hydroxyapatite Ca5(PO4)3(OH)
      Apatite Ca10(PO4)6(OH,F,Cl,Br)2
      Tetracalcium phosphate (CAS#1306-01-0): Ca4(PO4)2O


      Clinical significance


      Calcium phosphate stones account for approximately 15% of kidney stone disease. Calcium phosphate stones tend to grow in alkaline urine, especially when Proteus bacteria are present. It is the most common type in pregnant women.
      Calcium phosphate is the usual constitution of microcalcifications of the breast, particularly dystrophic calcifications. Microcalcifications as can be seen on mammography can be an early sign of breast cancer. Based on morphology, it is possible to classify by radiography how likely microcalcifications are to indicate cancer.











      References

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    Calcium phosphate - Wikipedia

    The term calcium phosphate refers to a family of materials and minerals containing calcium ions (Ca 2+) together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well.

    Calcium phosphate: What is it and what are the risks? - Medical News Today

    Jan 21, 2022 · Calcium phosphate is a compound containing calcium and phosphorus. It is naturally present in the body, and some people may take it as a supplement to increase their calcium intake.

    Calcium Phosphate: How Does It Work? - WebMD

    May 14, 2023 · Calcium phosphate is most often used to treat calcium deficiencies in your diet. However, there are several things you need to know before adding this supplement to your daily regimen. About ...

    Calcium phosphate, tribasic Uses, Side Effects & Warnings - Drugs.com

    Jun 26, 2024 · What is calcium phosphate? Calcium phosphate (tricalcium phosphate) is a mineral that is used as a supplement in people who do not get enough calcium from food. Calcium phosphate is used to treat calcium deficiencies that may be associated with low blood calcium, a parathyroid disorder, or osteoporosis and other bone conditions.

    Calcium Phosphate | Ca3(PO4)2 | CID 24456 - PubChem

    Calcium Phosphate | Ca3(PO4)2 or Ca3O8P2 | CID 24456 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

    Should You Take Calcium Phosphate? - Healthline

    Jul 21, 2018 · The kind of calcium in your bones and teeth is calcium phosphate, a compound of calcium and phosphorous. Learn whether this means taking calcium phosphate supplements can give you healthier...

    Calcium Phosphate: Benefits, Uses, and Dosage Guidelines

    Calcium Phosphate is a mineral supplement commonly used to treat or prevent low calcium levels in the body. It is often prescribed for conditions such as osteoporosis, bone fractures, and calcium deficiency.

    Understanding Calcium Phosphate: Composition & Applications

    Calcium phosphate refers to a family of materials and minerals containing calcium ions and phosphate ions. The most common form is hydroxyapatite, represented by the chemical formula Ca3(PO4)2. In pure form, it consists of calcium, phosphorus, and oxygen, which together contribute to its structural integrity and utility.

    Calcium Phosphate - Ca3(PO4)2 - BYJU'S

    Calcium phosphate is used to prevent and treat calcium deficiencies. Calcium phosphate may also be used for purposes not specified in this drug guide. Solubility is conventionally described as the quantity of a solid that can dissolve into a unit volume of solution.

    Calcium Phosphate - Encyclopedia.com

    Calcium Phosphate OVERVIEW. The three forms of calcium phosphate (KAL-see-um FOSS-fate) all occur as tasteless, odorless, colorless to white crystalline or powdery solids. Dibasic calcium phosphate, CaHPO 4, is also called calcium monohydrogen