• Source: Loganin

Loganin is one of the best-known of the iridoid glycosides. It is named for the Loganiaceae, having first been isolated from the seeds of a member of that plant family, namely those of Strychnos nux-vomica. It also occurs in Alstonia boonei (Apocynaceae), a medicinal tree of West Africa and in the medicinal/entheogenic shrub Desfontainia spinosa (Columelliaceae) native to Central America and South America.




Biosynthesis


Loganin is formed from loganic acid by the enzyme loganic acid O-methyltransferase (LAMT). Loganin then becomes a substrate for the enzyme secologanin synthase (SLS) to form secologanin, a secoiridoid monoterpene found as part of ipecac and terpene indole alkaloids.




References

Kata Kunci Pencarian:

• Loganin
• Secologanin synthase
• Loganiaceae
• Glycoside
• Loganic acid
• Loganate O-methyltransferase
• Secologanin
• 7-deoxyloganin 7-hydroxylase
• Sarracenin
• Triosteum