• Source: LPAR2

Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).




Function


This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.




Interactions


LPAR2 has been shown to interact with TRIP6.




Evolution






= Paralogues

=
Source:

LPAR1
LPAR3
S1PR1
S1PR5
S1PR4
S1PR2
S1PR3
GPR6
GPR3
GPR12
MC4R
MC5R
CNR1
MC3R
CNR2
MC1R
GPR119
MC2R




See also


Lysophospholipid receptor




References






Further reading






External links


"Lysophospholipid Receptors: LPA2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-05.
Lysophospholipid+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/2
• LPAR2
• Lysophosphatidic acid receptor
• List of human protein-coding genes 2
• Cannabinoid receptor 1
• Rhodopsin-like receptors
• Melanocortin 1 receptor
• Cannabinoid receptor 2
• Lysophosphatidic acid
• S1PR1
• LPAR1